Enclosed production line

​

#CHANSE dry tablet line flowchart #

CHANSE, as a total solution for pharmaceutical technology, is committed to solving customizable closed production lines in order to ensure the quality and safety of pharmaceutical products.

CHANSE's dry tablet containment line for solid dosage forms consists of the following equipment: closed weighing hoods, production line...

CHANSE's dry tablet containment line in the solid dosage section mainly consists of the following equipment: closed weighing hoods, dry granulators, elevated vacuum discharging systems, tablet presses, coating machines, capsule machines, washing machines and so on.

Related products available from #CHANSE#

airtight weighing enclosure

Dry Granulator

Dry granulator is a kind of granulation equipment which integrates the functions of raw material pre-pressure conveying, roll forming and extrusion granulation, which can be widely used in pharmaceutical, food and chemical industries.

Dry pelletizing machine is a kind of pelletizing equipment which integrates raw material powder pre-pressure conveying-roll forming-extrusion pelletizing. According to the domestic and foreign market demand, on the basis of absorbing foreign advanced technology, our company independently developed dry granulator has the following advantages:

①This equipment can make the powder material into granule of required mesh (>16 mesh), which increases the specific gravity and fluidity of the material;

②Through the screw horizontal feeding mode, pressure roller cooling and vacuum exhaust system, it effectively reduces the fine powder content of the finished product, improves the pressing quality of the drug, and provides good material preparation for the subsequent tablet pressing and capsule filling;

③The equipment has strong applicability to various materials, the granulation process does not use any additives, and can be made according to different needs of the required mesh size of the particles; has a simple process, large production batch, easy to clean and maintain and so on;

④This equipment can be used in pharmaceutical, food, chemical and other industries.

⑤ CHANSE can customize the design for this product to meet the needs of pharmaceutical production of OEB4 grade or above.

Elevating feeding machine

Elevating feeding machine has fixed type and mobile type, mainly used for pharmaceutical enterprises to convey solid materials such as powder, granular material feeding. Can be used with mixer, granulator, tablet press, coating machine, capsule filling machine and packaging machine and other process equipment, can effectively reduce cross-pollution and dust, reduce the labor intensity, and the material is not stratified, is the ideal material handling equipment for pharmaceutical factories, and at the same time, in the chemical industry, light industry, food and other industries can also be widely used.

Hermetic tablet presses

The hermetic tablet press has the following advantages:

① The main pressure and pre-pressure are 100 kN: the rotary table can be quickly dismantled and replaced to meet CIP; independent intellectual property rights, with 5 patents;

② Filling depth and tablet thickness adjustment are adopted servo control system and measuring device of international famous brand, with high positional accuracy;

③Adopting pressure sampling system of famous German brand and advanced control mode of Germany Siemens, the tablet weight precision can reach +1.5%;

④The tablet press chamber is isolated from the outside world and separated from the transmission area by adopting a fully enclosed, dust-proof structure;

⑤ Conforms to FDA and Union GMP: it can meet the isolation design of OEB4 grade or above.

Highly efficient coating machines

CHANSE self-developed coating machine has the following advantages:

①Suspended coating pot to eliminate cross-contamination;

② Shark-fin type stirring paddles, avoiding knocking edges and fragments of tablets;

③ Unique design of exhaust air flow blocking wing, reducing 25% energy loss;

④ Uniform and stable airflow structure, high consistency of tablet coating quality;

⑤ The world's most advanced spray gun atomization system maintains stable liquid supply and atomization, and CIP automatically clears the gun;

⑥ Precise temperature and humidity control, full coverage of CIP automatic cleaning system.

(For more details, please contact us)

Address：No.581 East Labor Road, Tianning District, Changzhou City, Jiangsu Province, China

Tel：0519-8550 5268

Fax: 0519-8886 9251

E-mail: sales@chansemt.com

Zip code: 213000

Website: www.chansemt.com

CHANSE Technology (Jiangsu) Co., Ltd (hereinafter referred to as “CHANSE Technology”) is a total solution provider of pharmaceutical technology, and the corporate motto of CHANSE Technology is: “Innovate, Pursue Excellence, Create Standards, Serve Customers”. “CHANSE Technology has three major business segments: pharmaceutical solid dosage forms, biologics and complex liquid dosage forms, and disposable biotechnology. Based on the equipment of “perfect design, elaborate manufacturing”, the solid drug preparation section actively provides a full set of technical support from process mapping, process optimization to process transfer and amplification for the majority of pharmaceutical customers; the biologics and complex liquid preparation section focuses on the biopharmaceutical, blood products and complex injection industry, adhering to the combination of process and engineering mode, and is committed to providing customers with the best service. The biologics and complex liquid preparations section focuses on the biopharmaceutical, blood products and complex injectables industries, and adheres to the model of process and engineering, and is committed to providing customers with the overall solution of the process system for the preparation of the stock solution and the production of the preparation; the disposable biotechnology section specializes in the research and development and production of clean and safe disposable biopharmaceutical use systems. Based on the leading technology, and taking “the deep integration of information technology and pharmaceutical technology” as the focus point, CHANSE has created the intelligent production line of “continuous manufacturing and data release” with the help of various advanced process analysis technologies (PAT) and self-developed intelligent production execution system (Smart MES). After more than 10 years of precipitation, the quality and performance of the equipment developed by CHANSE Technology has reached the international advanced level, and CHANSE Technology now has more than 700 square meters of process laboratories, which can provide more than 200 different varieties of supporting process services every year. In recent years, CHANSE Technology has been working together with customers to develop comprehensive solutions for digitalization, informatization and intelligence in the pharmaceutical field, to meet the challenges of “Industry 4.0” and “Made in China 2025”, and to help customers to develop their pharmaceutical manufacturing processes by virtue of advanced equipment performance, excellent process understanding and engineering advantages. With advanced equipment performance, excellent process understanding and engineering advantages, we help China's pharmaceutical industry to realize industrialization upgrading, cost reduction and efficiency.